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: Evaluation of the early effect of drugs in patients with neurological damage

: Evaluation of the early effect of erythropoietin and testosterone in patients with neurological damage

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170105031787N5
Enrollment
60
Registered
2023-05-01
Start date
2022-04-21
Completion date
Unknown
Last updated
2023-05-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neurological damage caused by brain trauma. Other disorders of nervous system

Interventions

Intervention 1: Intervention group: Patients will receive erythropoietin+testosterone (56,000 units subcutaneously) once a week for a maximum of three doses. Patients will receive the first dose of er

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients over 12 years Patients with neurological damage caused by brain trauma on radiograph or electroencephalogram with a GCS score of less than 9

Exclusion criteria

Exclusion criteria: Patients over 60 years Patients with fractures of other body parts Patients with fractures of other organs and other problems requiring surgical intervention, such as internal bleeding, rupture of internal organs, severe chest trauma in the medical record or radiographic view. Patients with spinal cord trauma Suffering from a dangerous trauma other than head trauma, including internal bleeding, systolic blood pressure drop less than 80 mmHg, and chest trauma within the first 24 hours.

Design outcomes

Primary

MeasureTime frame
Level of consciousness. Timepoint: Before the intervention and 1 week after the intervention. Method of measurement: Glasgow coma criteria.;Deep venous thrombosis of the lower limb. Timepoint: After intervention. Method of measurement: Based on ultrasound.;Frequency of deaths. Timepoint: After intervention. Method of measurement: Based on the information in the patient's record.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactVahid Ghorbani

Iran University of Medical Sciences

vahid_ghorbanikj91@yahoo.com+98 21 6741575

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026