Evaluation of drugs combination in patients with kidney stones

Comparative study of drug combination (morphine-granisetron) with (morphine-placebo) in patients with kidney stones for the control of pain and nausea and vomiting

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170105031787N4

Enrollment

120

Registered

2019-08-18

Start date

2019-09-16

Completion date

Unknown

Last updated

2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Renal colic. Unspecified renal colic

Interventions

Intervention 1: Intervention group: 0.1 mg / kg morphine sulfate intravenously, Simultaneously, Patients will receive a 5 cc syringe containing 40 mg / kg of intravenous granisetron. Intervention 2:

Eligibility

Sex/Gender

All

Age

16 Years to No maximum

Inclusion criteria

Inclusion criteria: Emergency medicine specialist diagnoses renal colic No history of allergy to granisetron if mentioned by the patient or a partner Possibility of getting IV Line

Exclusion criteria

Exclusion criteria: Patient unwillingness to continue treatment and follow-up Age under 16 years

Design outcomes

Primary

Measure	Time frame
Severity of pain. Timepoint: At the beginning of the injection, half an hour and one hour after the injection. Method of measurement: Visual Analogue Score.;Severity of nausea. Timepoint: At the beginning of the injection, half an hour and one hour after the injection. Method of measurement: Based on the patient's statement.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad-Reza Yasinzadeh

Iran University of Medical Sciences

yasinzadeh.mr@iums.ac.ir+98 21 6652 5327

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026