Ischemic stroke. Cerebral infarction
Conditions
Interventions
Intervention 1: First intervention group: Injection of two vitamins D 3 with a dose of 300,000 units. The first dose is taken after confirmation vitamin D deficiency at the beginning of the disease, a
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with vitamin D deficiency (less than 20 ng per ml) Patients with moderate acute stroke based on the NIHSS scoring system
Exclusion criteria
Exclusion criteria: The serum level of vitamin D is above 20 ng per ml Receive antioxidants (such as vitamins C and E) continuously Receive continuous anti-inflammatory drugs (steroids-NSAIDs) AIDS and neurodegenerative diseases (such as Alzheimer's, Parkinson's, ALS, MS Systemic diseases like, Diabetes Mellitus, Kidney Failure, Malignant Melanoma, Uremia, Liver Cirrhosis and Chronic Myocardial Infarction, Myopathy Change in mental status with unknown etiology
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The level of Tumor necrosis factor alpha. Timepoint: At the beginning of the study (before the intervention), 1 month after the start of taking vitamin D. Method of measurement: Blood sample.;The level of Interleukin 6. Timepoint: At the beginning of the study (before the intervention), 1 month after the start of taking vitamin D. Method of measurement: Blood sample.;The level of vitamin D. Timepoint: At the beginning of the study (before the intervention), 1 month after the start of taking vitamin D. Method of measurement: Blood Sample. | — |
Secondary
| Measure | Time frame |
|---|---|
| National Institues of Health Stroke Scale Measurement. Timepoint: At the beginning of the study (before the intervention), 1 and 3 months after the start of taking vitamin D. Method of measurement: National Institues of Health Stroke Scale Questionnaire.;Measuring Mini Mental State Examination. Timepoint: At the beginning of the study (before the intervention), 1 and 3 months after the start of taking vitamin D. Method of measurement: Mini Mental State Examination Questionnaire.;Measuring Modified Rankin Scale. Timepoint: At the beginning of the study (before the intervention), 1 and 3 months after the start of taking vitamin D. Method of measurement: Modified Rankin Scale Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLeila Simani
Shahid Beheshti University of Medical Sciences
Outcome results
None listed