Skip to content

Comparison of the Effectiveness of the Unified Protocol for Transdiagnostic Treatment and Cognitive Behavioral Therapy (CBT) in Improving Severe Health Anxiety

Comparison of the Effectiveness of the Unified Protocol for Transdiagnostic Treatment (UP) and Cognitive Behavioral Therapy (CBT) on Emotional, Behavioral and Cognitive Components in Patients with Illness Anxiety Disorder Comorbid with Depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170104031765N2
Enrollment
50
Registered
2023-11-14
Start date
2023-11-22
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

illness anxiety disorder. Hypochondriacal disorders

Interventions

Intervention 1: Intervention group: the people of the experimental group or integrated meta-diagnostic therapy group during 12 group sessions of approximately 60 to 90 minutes. All sections are perfor
The second session: Providing psychological training
The third and fourth sessions: Emotional awareness training
The fifth session: cognitive reassessment
The sixth session: Identifying avoidance patterns
the Seventh session: Emotion-induced behaviors (EDBs)
Eighth session: awareness and tolerance of physical feelings
9th and 11th sessions: introception and situational expouser and 12th session: relapse prevention. Treatment sessions will also be offered to clients by targeting treatment goals and focusing on diffe

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Primary diagnosis of illness anxiety disorder according to the Diagnostic and Statistical Manual of Mental Disorders 5 (DSM-5) Diagnosis of major depressive disorder (MDD), persistent depressive disorder (PDD) based on DSM-5 criteria Ages 18 to 65 years Able to read and write Not taking psychiatric drugs or in the case of taking antidepressants and anti-anxiety drugs for at least two months before the onset of interventions, the drug dose must be constant and the patient must agree to the drug dose remaining constant during the study

Exclusion criteria

Exclusion criteria: Patients with psychotic disorders Patients with bipolar disorder Patients with depressive disorder with psychotic symptoms Patients with a history of drug use in the last 6 months Patients at risk of suicide Personality disorder making the treatment procedure very difficult Patients with eating disorders Having a history of incurable physical illness such as cancer The need to change, stop or increase the drug dose or start a new drug after pre-test evaluations Receiving other psychological treatments in the past 5 years

Design outcomes

Primary

MeasureTime frame
Health anxiety score in Salkowski questionnaire. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Health Anxiety Questionnaire - Short Form (SV-HAI).;Depression score in Beck questionnaire. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Beck Depression Inventory - Second Edition (BDI-II).

Secondary

MeasureTime frame
The score of cognitions related to health anxiety. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Health Cognition Questionnaire (HCQ).;Anxiety Sensitivity Score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Anxiety sensitivity index-3 (ASI-3).;Distress Tolerance Score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Distress Tolerance Scale (DTS).;Emotion Regulation Score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Emotion regulation Questionnaire (ERQ).;Beck anxiety score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Beck Anxiety Inventory (BAI).;Cyberchondria Score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Short-Form- Cyberchondria Severity Scale (12-CSS).;Score different aspects of illness behavior. Timepoint: Before and after interventions and three month follow-up. Method of measurement: The Scale for the Assessment of Illness Behaviour (SAIB).;Interoceptive Attention Score. Timepoint: Before and after interventions and three month follow-up. Method of measurement: Interoceptive Attention Scale.;Amount of credibility/expectancy of improvement. Timepoint: After interventions. Method of measurement: Credibility/Expectancy Questionnaire (CEQ).;The rate of therapeutic alliance. Timepoint: After interventions. Method of measurement: Working Alliance Inventory (WAI) For assessing therapeutic alliance.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamid Mohsenabadi

Iran University of Medical Sciences

mohsenabadi.h@iums.ac.ir+98 21 6655 1655

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026