premenstrual syndrome. Premenstrual tension syndrome
Conditions
Interventions
Intervention 1: curcumin 100 mg oral capsules, twice a day (from a week before mense till 3 days after bleeding)for 3 months + aerobic exercise with 50-60 % maximum heart rate, 3 times a week, 1 hour
Treatment - Drugs
Placebo
Lifestyle
curcumin 100 mg oral capsules, twice a day (from a week before mense till 3 days after bleeding)for 3 months + aerobic exercise with 50-60 % maximum heart rate, 3 times a week, 1 hour each day, for 3
curcumin
100 mg oral capsules
twice a day(from a week before mense till 3 days after bleeding)
for 3 months
Corn starch
100 mg oral capsules
twice a day(from a week before mense till 3 days after bleeding)
for 3 months
Do aerobic exercise with 50-60 % maximum heart rate, 3 times a week, 1 hour daily, for 3 months
Sponsors
Vice Chancellor for research of Islamic Azad University Central Tehran Branch
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 18-35 year old; Having regular menstrual cycles ( 28-35 days); Suffering from moderate or severe PMS and at least have five physical symptoms based on Dickerson questionnaire; Do not Consumption effective drugs (chemical or herbal) on the premenstrual syndrome in the recent quarter. Exclusion criteria: physical and mental illnesses like diabetes, biliary or kidney disease, epilepsy, thyroid disease or other metabolic disorders; Consumption hormonal, anti convulsants and anti depression drugs; Smoking and drug abuse.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Physical Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Emotional Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Psychological Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Prostaglandin E2. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Estrogen. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Progesteron. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Prolactin. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Blood suger. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Edema. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Physical Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Emotional Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Prolactin. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Progesteron. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Psychological Indicators of Premenstrual syndrome. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Blood suger. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Esterogen. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Prostaglandin E2. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements.;Edema. Timepoint: before intervention and 3 months after intervention. Method of measurement: Dickerson standard questionnaire , blood Measurements. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactLadan Zoodfekr
Islamic Azad University
Outcome results
None listed