Atrophy Vaginal in post menopausal women. Postmenopausal Atrophic Vaginitis
Conditions
Interventions
Intervention 1: Cream Vaginal Fenugrrek 5% one Applicator daily for 8 week. Intervention 2: control group (placebo) one applicator daily for 8week.
Treatment - Drugs
Placebo
Cream Vaginal Fenugrrek 5% one Applicator daily for 8 week
control group (placebo) one applicator daily for 8week
Sponsors
Vice chancellor for research, Ahwaz JundiShapur University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: inclusion criteria: Age between 45 to 65; Amenorrhea at less 12 month or have hormone test with FSH level more than 40 unit; Presenting symptom of vaginal atrophy; Have Sexual activity and single partner; Exclusion criteria; Vaginal infection? Genital Abnormalities? The use of Sex Hormones within the 8 weeks preceding studY; user of smoke and alcohol and etc; Genital Bleeding or spotting of unknown Cause; Use of Phytoestrogens such as Soy; Red clove; Fenugreek; Vitex within the last one Month.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of Maturity vaginal. Timepoint: Before and after eight weeks (end of intervention). Method of measurement: Vaginal smear.;Vaginal Atrophy. Timepoint: Before intervention, Two weeks after the intervention, Four weeks after intervention, Eight weeks after intervention. Method of measurement: Kupperman Index Questionnaire.;Vaginal PH. Timepoint: Before and after eight weeks (end of intervention). Method of measurement: By PH meter strips. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sexual function. Timepoint: Before and after intervention. Method of measurement: Female Sexual Function Index (FSFI) questionnaire.;Temperament. Timepoint: Before and after intervention. Method of measurement: Temperament questionnaires.;Dyspareunia. Timepoint: Before intervention, Two weeks after the intervention, Four weeks after intervention, Eight weeks after intervention. Method of measurement: self-assessed 4-point scale of composite score.;Menopausal symptoms. Timepoint: Before intervention, 2, 4, 8 weeks after intervention. Method of measurement: Kupperman Index Questionnaire.;Severity of menopausal symptoms. Timepoint: Before intervention, 2, 4, 8 weeks after intervention. Method of measurement: Menopause Rating Scale (MRS) questionnaire.;Sexual satisfaction. Timepoint: Before and after intervention. Method of measurement: Larson's sexual satisfaction questioner. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFakhriyeh Mazalzadeh
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed