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The effects of ORS with probiotics, zinc and vitamin A on diarrhea in children

Evaluation of The effect of ORS with probiotics, zinc and vitamin A on diarrhea in children, a double blind clinical trial

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017010312437N2
Enrollment
175
Registered
2017-08-17
Start date
2017-03-20
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute watery diarrhea. Gastroenteritis and colitis of unspecified origin

Interventions

Intervention 1: Intervention 1: oral administration of 20 mgr of zinc gluconate plus ORS in 4 sachets soluble in 250 ml of water daily. Intervention 2: Intervention 2: oral administration of 20000 IU
Treatment - Drugs
Intervention 1: oral administration of 20 mgr of zinc gluconate plus ORS in 4 sachets soluble in 250 ml of water daily
Intervention 2: oral administration of 20000 IU vitamin A plus ORS in 4 sachets soluble in 250 ml of water daily
Intervention 3: oral administration of 109 CFU probiotics plus ORS in 4 sachets soluble in 250 ml of water daily
Intervention 4: oral administration of 20 mgr of zinc gluconate,20000 IU vitamin A,109 CFU probiotics plus ORS in 4 sachets soluble in 250 ml of water daily
Control: oral administration of ORS in 4 sachets soluble in 250 ml of water daily

Sponsors

Takgene zist pharmacy company
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 5 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 1-5 years; Acute watery diarrhea Exclusion criteria: High fever (T>38.5°C); Severe dehydration; Bloody diarrhea; Severe malnutrition; Using of antibiotics or anti-diarrheal drugs; Patients with more than one complain; Immune deficiency

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Duration of diarrhea. Timepoint: Daily. Method of measurement: Asking from patient or mother.;Frequency of diarrhea. Timepoint: Daily. Method of measurement: Asking from patient or mother.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Reza Sharif

Kashan University of Medical Sciences

mrsharifmd@yahoo.com+98 31 5554 0026

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026