The effect of cognitive behavioral therapy (CBT) for reducing signs and symptoms of bipolar disorder

Comparison of the efficacy of drug therapy with cognitive-behavioral therapy with the drug in reducing the symptoms and sings of type 2 bipolar disorder.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20170103031741N2

Enrollment

Registered

2018-09-11

Start date

2018-06-10

Completion date

Unknown

Last updated

2018-10-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar Mood Disorder type one. F31

Interventions

Intervention 1: Intervention group : will be receive cognitive-behavioral therapy (12 sessions,Based on JC Wright method) with a common drug treatment such as sodium valproate (15mg/kg/Daily, PO) and

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age minimum 18 years and maximum 50 years Minimum education third grade middle school Minimum standards DSM-V criteria for the diagnosis of bipolar disorder type People who experience a first episode of disease Chronic patients who had at least 2 weeks of discontinuation And a new episode of recurrent disease and had been hospitalized.

Exclusion criteria

Exclusion criteria: Having substance abuse Having active thoughts of suicide Having any comorbidity disorder accompanied by a psychotic clinical presentation. Having OCD Having any personality disorder. Having impulse control disorder and aggression. Any pregnant. History of any psychiatric treatment in the past 6 months. Hospitalized patients have a history of drug treatment without discontinuing the drug.

Design outcomes

Primary

Measure	Time frame
High Mood. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Sexual interests. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Sleep. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Thought content. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Aggressive behavior. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Irritability. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Speech impairment. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Appearance. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Insight. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Motor activity. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Speech speed. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.	—

Measure

Time frame

High Mood. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Sexual interests. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Sleep. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Thought content. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Aggressive behavior. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Irritability. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Speech impairment. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Appearance. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Insight. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Motor activity. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.;Speech speed. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: Yang Mania Scale Response; Hamilton Test.

—

Secondary

Measure	Time frame
Quality of life. Timepoint: At the beginning of the study and 2 months after the intervention. Method of measurement: FS36 Score.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mehryar Nadermohammadi

Ardabil University of Medical Sciences

m.nadermohammadi@arums.ac.ir+98 45 3324 2400

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026