Head Trauma. Superficial injury of head
Conditions
Interventions
Intervention group 2: Intravenous Ondansetron, 4mg/2ml, Once injection
Intervention group 1: Intravenous Metoclopramide, 10 mg/2ml once injection
Intervention 1: Intervention group 1: Intravenous Metoclopramide, 10 mg/2ml once injection. Intervention 2: Intervention group 2: Intravenous Ondansetron, 4mg/2ml, Once injection.
Treatment - Drugs
Sponsors
Vice chancellor for research, Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: History of head trauma; Presence of nausea or vomiting; Triage level of 3 or more; GCS >=13, age over 15. Exclusion criteria: Unstable hemodynamics; Pregnancy or breast feeding; Neurologic deficit; Restless leg syndrome; Alcoholism; Prior use of antiemetics within 8 hours; Opioid use; Prior intravenous fluid administration; Vertigo; Chemotherapy; Radiotherapy; History of allergy or adverse reaction to metoclopramide or ondansetron; inability to complete trial or record outcomes.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea / Vomiting. Timepoint: Before and 20 minutes after injection. Method of measurement: VAS score (visual analog scale). | — |
Secondary
| Measure | Time frame |
|---|---|
| Drug adverse effect including extrapyramidal effects, dyskinesia. Timepoint: at discharge. Method of measurement: clinical exam.;Need for repeating injection. Timepoint: 20 minutes after first injection. Method of measurement: VAS score (Visual Analog Scale). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHosein Partovinejad
Shahid Beheshti University of Medical Sciences
Outcome results
None listed