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The effect of vitamin D supplementation in the prevention of recurrence of preeclampsia in pregnant women with a history of preeclampsia

The effect of vitamin D supplementation in the prevention of recurrence of preeclampsia in pregnant women with a history of preeclampsia

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2017010131695N1
Enrollment
142
Registered
2017-01-29
Start date
2017-01-09
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preeclampsia. Gestational [pregnancy-induced] hypertension with significant proteinuria Excl.: superimposed pre-eclampsia (O11) O14.0 Moderate pre-eclampsia O14.1 Severe pre-eclampsia

Interventions

Intervention 1: Intervention 1 : Administration of Vitamin D3, 50000 IU ,pearl. Intervention 2: intervention 2: Administration of placebo.
Prevention
Treatment - Drugs
Intervention 1 : Administration of Vitamin D3, 50000 IU ,pearl
intervention 2: Administration of placebo

Sponsors

Vice chancellor for research, Kurdistan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : pregnancy , history of preeclampsia in a previous pregnancy , blood levels of vitamin D above 32 nanograms per milliliter Exclusion criteria : the risk of chronic hypertension before pregnancy , chronic kidney disease associated pulmonary and cardiovascular , immunological diseases such as lupus , the uncertainty of patient cooperation in the study , immigration or study leave.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Systolic and Diastolic blood pressure. Timepoint: In initiation of study, 2 week after intervention, per 2 week to termination of pregnancy. Method of measurement: Blood pressure is measured in the sitting position by using mercury barometer.;Proteinuria. Timepoint: If there is a blood pressure greater than or equal to 140/90 mm Hg. Method of measurement: laboratory kit.

Secondary

MeasureTime frame
Preeclampsia Recognition. Timepoint: After 28 weeks of pregnancy. Method of measurement: Measurement of blood pressure by using barometer, clinical symptoms and proteinuria detection by using laboratory kit.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShole Shah Gheibi

Besat Hospital, Sannandaj

shahgheibi@yahoo.com+98 87 3328 2001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 27, 2026