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The efficacy of Ondansetron and Granisetron in preventing of post Laparascopic Cholesystectomy nausea and vomiting

The efficacy of Ondansetron and Granisetron in preventing of post Laparascopic Cholesystectomy nausea and vomiting (PONV)

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20170101031697N2
Enrollment
90
Registered
2019-06-25
Start date
2016-03-20
Completion date
Unknown
Last updated
2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nausea and vomiting. Nausea and vomiting

Interventions

Intervention 1: First intervention group: Patients in this group received 2 mg of Granisetron (in a total volume of 10 ml), 5 minutes before induction of anesthesia. Intervention 2: Second interventio

Sponsors

Bandare-abbas University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients with ASA grade one Patients with ASA grade two Patient were referred for laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: Febrile illness History of infection Pulmonary disease Allergy to Endonestrone Allergy to Granisetron History of seizure History of vascular contraction Intracranial pressure History of drug abuse Patients who do not have proper collaboration during the study History of digestive disease Emergency patients Patients with a history of motion sickness (PTSD) or motion sickness (PONV) have a history of nausea and vomiting Surgery Patients with history of nausea and vomiting during previous surgery Patients who received anti-nausea and vomiting before surgery Patients with hypothermia (below 36 ° C) Pregnancy Inability to perceive VAS criteria for pain The patient's consent for participation in the study Weight more than 120kg Weight less than 50kg

Design outcomes

Primary

MeasureTime frame
Nausea and vomiting. Timepoint: Patients were monitored for nausea and vomiting during recovery and after recovery for 24 hours during the hours (2-4-6-12-24). Method of measurement: According to Clinical Obstetrician Anesthesiologist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaid Kashani

Bandare-abbas University of Medical Sciences

Sdkashani486@gmail.com+98 76 3334 5009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026