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The effect of scaling on the concentrations of inflammatory factors in patients with gum diseases

The effect of phase I periodontal treatment on the concentrations of IL-22 and S100A12 in patients with chronic periodontitis

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016123131687N1
Enrollment
22
Registered
2017-04-15
Start date
2017-03-10
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic periodontitis. Chronic periodontitis

Interventions

Intervention :scaling & root planning and oral hygiene control
The GCF of the patients after and before phase I periodontal treatment , are the case and control groups respectly..
Treatment - Other
The GCF of the patients after and before phase I periodontal treatment , are the case and control groups respectly.

Sponsors

Vice chancellor for research,Dental faculty of Shahed university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The inclusion criteria : presence of at least 20 teeth in the oral cavity; affliction with moderate and severe chronic periodontitis with radiographic evidence of bone loss The exclusion criteria : patients with cardiovascular diseases and hypertension; use of tobacco; pathologic conditions in the oral cavity; subjects with chronic inflammatory conditions such as rheumatoid arthritis; presence of tumors; pregnancy; use of any medications affecting the periodontium; presence of systemic diseases that affect the course of periodontal disease; having undergone scaling and root planing during the previous 6 months; history of taking antibiotics and Nonsteroidal anti-inflammatory drug during the previous 3 months

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
S100A12. Timepoint: base line,4 weeks. Method of measurement: ELISA TEST.;IL22. Timepoint: base line,4 weeks. Method of measurement: ELISA TEST.

Secondary

MeasureTime frame
Clinical attachment level. Timepoint: base line, 4 weeks. Method of measurement: by williams probe( clinical).;Clinical probing depth. Timepoint: base line , 4 weeks. Method of measurement: by williams probe ( clinical).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRazieh Nejadi

Dental faculty of Shahed university

dr.nejadi@gmail.com; r.nejadi@shahed.ac.ir+98 21 2654 1610

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026