The effect of exercise training on myokines and blood lipids

Effects of aerobic, resistance and concurrent training on Irisin, Myostatin, blood lipids, glucose homeostasis, Physical fitness and body composition in Inactive girls

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016123125449N2

Enrollment

Registered

2017-01-24

Start date

2015-12-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy Inactive normal or overweight girls. Lack of physical exercise

Interventions

Intervention 1: control group Continued their usual activities. Intervention 2: Aerobic training 8 weeks, 3 sessions per week, each session 65 min (10 min warm up, 50 min aerobic training and 5 min co

control group Continued their usual activities

Aerobic training 8 weeks, 3 sessions per week, each session 65 min (10 min warm up, 50 min aerobic training and 5 min cool down), using 65-75 Percent of maximum heart rate (220-age)

resistance training 8 weeks, 3 sessions per week, each session 65 min (10 min warm up, 50 min resistance training, 5 min cool down), using 65-75 percent of 1RM, 2-4 set, 9 training, 8-12 repetition w

concurrent training 8 weeks, 3 sessions per week, each session 65 min (10 min warm up, 25 min resistance training, 25 min aerobic training and 5 min cool down)

Eligibility

Sex/Gender

Female

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: be girl; aged of 20-35 years; not have regular exercise training during last year; not have cardiovascular or orthopedic disease; have normal or overweight Exclusion criteria: absence for four sessions

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Myostatin. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using immunoassay method (ng/l).;Irisin. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using immunoassay method (µg/ml).;Cholesterol. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using photometric method (mg/dl).;Triglyceride. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using photometric method (mg/dl).;LDL. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using enzymatic method (mg/dl).;HDL. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using enzymatic method (mg/dl).;Added at 2017-01-24: Insulin resistance. Timepoint: Added at 2017-01-24: before and after training period. Method of measurement: Added at 2017-01-24: using HOMA method.;Added at 2017-02-26: Insulin. Timepoint: Added at 2017-02-26: Before intervention and 24 hours after last training session. Method of measurement: Added at 2017-02-26: serum levels using immunoassay method (pmol/l).;Added at 2017-02-26: Fast blood Sugar. Timepoint: Added at 2017-02-26: Before intervention and 24 hours after last training session. Method of measurement: Added at 2017-02-26: serum levels using photometric method (mg/dl).	—

Measure

Time frame

Myostatin. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using immunoassay method (ng/l).;Irisin. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using immunoassay method (µg/ml).;Cholesterol. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using photometric method (mg/dl).;Triglyceride. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using photometric method (mg/dl).;LDL. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using enzymatic method (mg/dl).;HDL. Timepoint: Before intervention and 24 hours after last training session. Method of measurement: serum levels using enzymatic method (mg/dl).;Added at 2017-01-24: Insulin resistance. Timepoint: Added at 2017-01-24: before and after training period. Method of measurement: Added at 2017-01-24: using HOMA method.;Added at 2017-02-26: Insulin. Timepoint: Added at 2017-02-26: Before intervention and 24 hours after last training session. Method of measurement: Added at 2017-02-26: serum levels using immunoassay method (pmol/l).;Added at 2017-02-26: Fast blood Sugar. Timepoint: Added at 2017-02-26: Before intervention and 24 hours after last training session. Method of measurement: Added at 2017-02-26: serum levels using photometric method (mg/dl).

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Secondary

Measure	Time frame
VO2max. Timepoint: Before and after training period. Method of measurement: using Bruce Treadmill test (ml/kg/min).;Steight. Timepoint: Before and after training period. Method of measurement: using 1RM test (kg).;Added at 2017-01-24: Body composition. Timepoint: Added at 2017-01-24: before and after training period. Method of measurement: Added at 2017-01-24: using body mass index and waist to hip ratio.	—

Measure

Time frame

VO2max. Timepoint: Before and after training period. Method of measurement: using Bruce Treadmill test (ml/kg/min).;Steight. Timepoint: Before and after training period. Method of measurement: using 1RM test (kg).;Added at 2017-01-24: Body composition. Timepoint: Added at 2017-01-24: before and after training period. Method of measurement: Added at 2017-01-24: using body mass index and waist to hip ratio.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Izaddoust

Islamic Azad University Rasht Branch

shabani@iaurasht.ac.ir+98 13 3385 6174

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026