The effect of voice therapy on treatment of patients with spasmodic dysphonia after Botox injection

Comparison the Effects of Modified Combined-Modality Treatment approach with Botox-Injection on Voices of Patients with Adductor Spasmodic Dysphonia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016122926499N2

Enrollment

Registered

2017-01-16

Start date

2016-11-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Adductor Spasmodic Dysphonia. Condition 2: Adductor Spasmodic Dysphonia. Other and unspecified voice disturbances Idiopathic and orofacial dystonia,

Interventions

Intervention 1: Intervention group: Combined0modality approach which consists of Botox injection and 10 Semi-intensive Voice Therapy. Each session lasts for 30 minutes. The injection will apply bilate

Rehabilitation

Treatment - Surgery

Intervention group: Combined0modality approach which consists of Botox injection and 10 Semi-intensive Voice Therapy. Each session lasts for 30 minutes. The injection will apply bilaterally to both T

Control Group: They receive Botox injection. Both Thyroarytenoid muscles will be injected. THey will not recieve any Voice THerapy after injection.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion: all patients with adductor Spasmodic Dysphonia; No history of Botox injection Exclusion: presence of any progressive CNS disorders; Dystonic signs in other part of the body

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Jitter. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Hertz.;Fundamental Frequancy. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Hertz.;Shimmer. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Percent.;Maximum Phonation Time. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Timer, Second.;Perceptual Voice Quality. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: GRBAS scale.;Voice Self-assessment score. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Voice Activity and Participation Profile- Persian Version.	—

Measure

Time frame

Jitter. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Hertz.;Fundamental Frequancy. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Hertz.;Shimmer. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Praat software, Percent.;Maximum Phonation Time. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Timer, Second.;Perceptual Voice Quality. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: GRBAS scale.;Voice Self-assessment score. Timepoint: before intervention, 1-3-6 months after intervention. Method of measurement: Voice Activity and Participation Profile- Persian Version.

—

Secondary

Measure	Time frame
Between Injections intervals. Timepoint: 6 month after intervention. Method of measurement: Month.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Faham

Iran University of Medical Sciences (IUMS)

Mfaham@iums.ac.ir+98 21 2222 8051

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026