Schizophrenia. Schizophrenia
Conditions
Interventions
Intervention 1: Intervention group: In this group, patients will receive 100 to 200 mg of modafinil per day for 4 weeks in addition to the prescribed antipsychotic treatment (resperidone or olanzapine
Sponsors
Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients diagnosed with schizophrenia based on DSM-5 criteria Schizophrenic patients who have been treated with risperidone or olanzapine.
Exclusion criteria
Exclusion criteria: Taking typical antipsychotic and atypical antipsychotic drugs, except for risperidone and olanzapine, and antidepressants, sodium valproate, lithium, and benzodiazepines. The presence of accompanying psychiatric disorders such as schizoaffective or other psychotic disorders, bipolar disorder, anxiety disorders such as panic disorder or obsessive-compulsive disorder, post-traumatic stress disorder, eating disorder Dependence or abuse of substances, drugs or alcohol, acutely or in the past 12 months, except for nicotine Allergy to Modafinil or any of the placebo ingredients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Negative symptoms. Timepoint: Before and 4 weeks after the study. Method of measurement: Scale for Assessment of Negative Symptoms (SANS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHatam Boostani
Ahvaz University of Medical Sciences
Outcome results
None listed