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Comparison of two ventilation methods "volume control & pressure control" on blood loss of posterior Spinal fixation surgery

Comparison of two ventilation methods "volume control & pressure control" on blood loss of posterior Spinal fixation surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016122731611N1
Enrollment
78
Registered
2017-03-18
Start date
2016-10-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fracture of lumbar vertebra. Fracture of lumbar vertebra

Interventions

Intervention 1: First group: during the surgery operation, volumetric ventilation was started with a current volume of 7 ml/kg/IBW, inspiration rate of 12 cycles per minute and inhale to exhale ratio
Treatment - Other
First group: during the surgery operation, volumetric ventilation was started with a current volume of 7 ml/kg/IBW, inspiration rate of 12 cycles per minute and inhale to exhale ratio of 1:2 without p
Second group: during the surgery operation, pressure ventilation with the initial pressure of 15 H2O/cm, inspiration rate of 12 cycles per minute and inhale to exhale ratio 1:2 with no peep drops down

Sponsors

Vice Chancellor for Research and Technology Kashan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients aged 18-75 with physical condition scored 1 or 2 from American Anesthesia Association nominated for elective-fusion posterior spine surgery operation in 3-4 levels, hospitalized for traumatic fracture of the lumbar spine. Exclusion criteria: Patients with cardiopulmonary disorders; uncontrolled hypertension and diabetes; SCI and coagulopathies patients and patients with BMI more than 35; or treated by aspirin; heparin and warfarin are excluded from the study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Surgical blood loss. Timepoint: End of surgery. Method of measurement: Calculating the amount of blood in the suction drain and bleed by ml accumulat.

Secondary

MeasureTime frame
Hypotension. Timepoint: During operation. Method of measurement: Continuous NIBP monitoring.;Surgeon's satisfaction of a bloodless field. Timepoint: At the end of surgery. Method of measurement: surgeon's satisfaction scoring system.;Number of infused Blood bags. Timepoint: At the end of surgery. Method of measurement: Counting the number of infused blood bags.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactManoochehr Salimian

Kashan University of Medical Sciences

Drmsr_44@yahoo.com+98 31 5554 0025

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026