A comparison between therapeutic effects of between Avocado soya and celecoxib on knee arthrosis

A comparison between Avocado+soya and celecoxib on serum levels of cartilage oligomeric matrix protein (COMP) in patients with knee osteoarthritis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201612271479N5

Enrollment

Registered

2017-01-10

Start date

2017-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis. Gonarthrosis [arthrosis of knee]

Interventions

Intervention 1: Intervention 1: Avocado + soy one tablet/daily for 2 months. Intervention 2: 1ntervention 2: celecoxin 200mg/daily for 2 months.

Treatment - Drugs

Intervention 1: Avocado + soy one tablet/daily for 2 months

1ntervention 2: celecoxin 200mg/daily for 2 months

Eligibility

Sex/Gender

All

Age

30 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1- Knee osteoarthritis according to ACR criteria 2- Age 30-80 years 3- Radiologically ascertained grade I or II of knee osteoarthritis on the Kellgren-Lawrence scale. Exclusion criteria: 1- Secondary osteoarthritis 2- Any history of intolerance to Avocado+ soya and celecoxib 3- Uncontrolled hypertension

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cartilage oligomeric matrix protein (COMP). Timepoint: At enrollment and every month up to 2 months. Method of measurement: ELISA assay.	—

Secondary

Measure	Time frame
Knee osteoarthritis symptoms. Timepoint: At enrollment and then every month up to months. Method of measurement: WOMAC questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Hassan Jokar

Imam Reza Hospital

jokarmh@mums.ac.ir+98 51 3859 8818

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026