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Efficacy of pramipexole treatment and methylphenidate in children with attention deficit hyperactivity disorder, compared with placebo and methylphenidate.

Efficacy of pramipexole treatment and methylphenidate in children with attention deficit hyperactivity disorder, compared with placebo and methylphenidate.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201612253979N6
Enrollment
10
Registered
2017-01-24
Start date
2017-02-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

attention deficit hyperactivity disorder. Disturbance of activity and attention

Interventions

Intervention 1: Intervention group: children treat with methylphenidate and pramipexole during 6 weeks. The starting dose of methylphenidate considered to be 0.3mg / kg in two divided doses and increa
Treatment - Drugs
Intervention group: children treat with methylphenidate and pramipexole during 6 weeks. The starting dose of methylphenidate considered to be 0.3mg / kg in two divided doses and increase to 1mg/kg bas
Treatment groups: children 6 weeks will be treated with methylphenidate and placebo. Placebo pill shape, color, smell and taste will be like pramipexole.

Sponsors

Research Devision, Ahvaz Jondishapoor Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children 6-12 years old;Having diagnostic criteria and testing Connors. Exclusion criteria: medical conditions such as kidney failure and epilepsy;psychiatric disorders with a focus on DSM IV-TR; mental disability;history of seizures other than seizures associated with fever,need for dopaminergic drugs, levodopa, ranitidine, cimetidine

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Attention Deficit Hyperactivity Disorder. Timepoint: Befor intervention- the end of second, fourth and sixth weeks of the study. Method of measurement: The Conner's parent rating scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactForough Riahi

Ahvaz Jundishapur University of Medical Sciences

riahi13@gmail.com+98 61 3374 3038

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026