Effect of preventive agents on oral health in orthodontic patients.

A Clinical Trial of Comparing The effect of Fluoride varnish and Chlorhexidine gel on white spots and gingival indexes in orthodontic patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016122531558N1

Enrollment

Registered

2017-06-24

Start date

2017-01-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Dental white spot lesion. Condition 2: Gingivitis. Caries limited to enamel Chronic gingivits

Interventions

Intervention 1: Intervention group 1: Fluoride varnish %5 which is made in USA will be applied on teeth every 3 months until 9 months. Intervention 2: Intervention group 2: Chlorhexidine gel 0/2% whi

Prevention

Intervention group 1: Fluoride varnish %5 which is made in USA will be applied on teeth every 3 months until 9 months.

Intervention group 2: Chlorhexidine gel 0/2% which is made in Spain,in dose of 5mg will be applied on teeth every 3 months until 9 months.

Placebo group: Sorbitol solution (70% W/W) will be applied on teeth every 3 month until 9 months.

Control group: No intervention is done.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: age over 18; permanent dentition in both jaws; Fixed appliances in both jaws at least 8 anterior teeth; Non extraction treatment. Exclusion criteria: Showing allergic reaction to used materials; history of previous orthodontic treatment; systemic disease affecting teeth such as Amelogenesis and Dentinogenesis Imperfecta; history of using drugs affecting plaque accumulation ,saliva secretion and gingiva; syndromes or systemic diseases associating with inflammatory processes (Licken planus,Lupus,Pemphigoid diseases); Patients who are not able to perform the hygiene instructions.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
White spots. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Visual inspection with intra oral examination mirror.;Gingival index. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Dental probe.;Plaque index. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Visual inspection.	—

Measure

Time frame

White spots. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Visual inspection with intra oral examination mirror.;Gingival index. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Dental probe.;Plaque index. Timepoint: Before the first intervention, 3, 6 and 9 months after that and before the intervention in each time. Method of measurement: Visual inspection.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNavid Yaraghi

Isfahan University of Medical Sciences

navidyaraghi@yahoo.com+98 31 3792 5543

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026