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Effectivness of autologous serum in corneal superficial layer healing

Effectivness of autologous serum in Corneal Epitelial defect healing

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016122531450N3
Enrollment
20
Registered
2017-05-26
Start date
2017-02-19
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refraction. Hypermetropia,Myopia,Astigmatism

Interventions

Intervention 1: Autologous serum eye drop 20% every 6hours(4times a day)until corneal epithelial defect healing.(intervention). Intervention 2: Conventional artificial tears every 6 hours(4times a day
Treatment - Drugs
Autologous serum eye drop 20% every 6hours(4times a day)until corneal epithelial defect healing.(intervention)
Conventional artificial tears every 6 hours(4times a day)until corneal epithelial defect healing.(control)

Sponsors

Nikookari Ophthalmology Research Center,Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria:minimum age 18; stable refraction for at least 1 year; normal corneal topography with minimum centeral thickness 500; stop useing daily wear lens at least 1 weak before; Exclosion criteria; unstable refraction;dry eye; belepharitis; corneal diesese; glaucoma; systemic diesese; abnormal topography and kratoconus

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Time to corneal epitelial healing. Timepoint: day 1.2.3. and 7. Method of measurement: slit lamp examination.

Secondary

MeasureTime frame
Pain. Timepoint: day1,2,3,7,month1. Method of measurement: check list.;Corneal opacity. Timepoint: day1,2,3,7 month1,6. Method of measurement: slit lamp.;Visual acuity. Timepoint: month1,6. Method of measurement: snelen chart.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSiamak Nejatbakhsh

Tabriz University of Medical Sciences

info@elibrary.tbzmed.ac.ir; dln@tbzmed.ac.ir+98 41 3335 5921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026