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The effect of Hyaluronic Acid and Triamcinolone in Oral Lichen Planus

The effect of intralesional injection of Hyaluronic Acid and Triamcinolone in Oral Lichen Planus

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201612241559N11
Enrollment
56
Registered
2017-01-16
Start date
2016-12-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral lichen planus. Lichen planus

Interventions

Intervention 1: Intervention: 7mg hyaluronic acid powder dissolved in one triamcinolone vial, via intralesionally injection, one time at the beginning of the treatment. Intervention 2: control: triam
Treatment - Drugs
Intervention: 7mg hyaluronic acid powder dissolved in one triamcinolone vial, via intralesionally injection, one time at the beginning of the treatment
control: triamcinolone, via intralesionally injection, one time at the beginning of the treatment

Sponsors

Private funding source
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Bilateral presence of white reticular-papular lesions; histopathological criteria such as hydropic (liquefactive) degeneration of basal layer; band-like infiltration of mononuclear inflammatory cells in the superficial connective tissue; erosive/ulcerative form of lesion and atrophic/erythematous form of lesion. Exclusion criteria: Dysplasia; systemic diseases; history of chemotherapy; history of radiotherapy; pregnancy and nursing; history of allergy to hyaluronic acid

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cure. Timepoint: 14 days and 28 days after intervention and then monthly up to 6 month. Method of measurement: clinical examination.;Recurrence. Timepoint: 14 days and 28 days after intervention and then monthly up to 6 month. Method of measurement: clinical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKhatereh Akbari

Dental faculty of Tehran Univercity of Medical Sciences

kh_akbari@yahoo.com+98 21 4423 3115

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026