Glaucoma. Primary open-angle glaucoma Glaucoma (primary)(residual stage): capsular with pseudoexfoliation of lens chronic simple low-tension pigmentary
Conditions
Interventions
Intervention 1: Intervention group 2: patients in this group will be put under general anesthesia. At first, a fornix-based conjunctival flap is created. Then, a 4x 4 mm outer parabolic flap, approxim
Treatment - Drugs
Intervention group 1: patients in this group will be put under general anesthesia. First, a fornix-based conjunctival flap is created. Then, a 4x 4 mm outer parabolic flap, approximately 200 µm thick,
Sponsors
Vice Chancellor for research of Tabriz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Inclusion criteria: The need for cataract surgery in patients with open-angle glaucoma that have glaucomatous progressive cupping and deterioration of the visual field; Diagnosis of open-angle glaucoma on maximally tolerated medical therapy with uncontrolled IOP; The need for cataract surgery in patients with open-angle glaucoma requiring multiple medications to control IOP; Patients suffering from glaucoma and cataract with impaired vision; Patients’ willingness to participate in the study. Exclusion criteria: Patients with contraindications to bevacizumab such as arterial thromboembolic events, uncontrolled hypertension, and congestive heart failure,..; Discernable congenital abnormality of the anterior chamber angle; Ocular infection; Previous ocular surgery; Uveitis; Corneal diseases that could affect IOP or its measurement such as corneal opacity, large pterygium, ...; Patients who are less than 40 years? Diabetes; Neovascular glaucoma? Patient with any systemic or ocular complication.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Goldmann applanation tonometry (mmHg). | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual acuity. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Snellen charts.;Visual field. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Humphrey 24-2 SITA Standard perimetry (HFA 24-2) Or(HFA 10-2).;Beleb morphology. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Moorfields Bleb Grading System.;Endophthalmitis. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Examination slitlamp.;Conjunctival necrosis. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Examination slitlamp.;Hypertension. Timepoint: Before surgery, 1 day, 3 days, 2 weeks, 4 weeks, 3 months and 6 months after surgery. Method of measurement: Sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAtena Latifi
Tabriz University of Medical Sciences
Outcome results
None listed