Comparative effect of two hamstring strengthening methods in patients with knee osteoarthritis

A comparative study of lateral hamstring strengthening versus overall hamstring strengthening on pain, disability, and quality of life, and foot loading pattern in patients with primary osteoarthritis and varus deformity: randomized clinical trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161221031506N5

Enrollment

Registered

2021-04-15

Start date

2021-04-04

Completion date

Unknown

Last updated

2021-04-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis. Unilateral primary osteoarthritis, unspecified knee

Interventions

Intervention 1: Intervention group: All hamstring therapy exercises in this group will be performed with external rotation of the tibia and the stretch will focus on medial hamstring muscle. Intervent

Eligibility

Sex/Gender

All

Age

30 Years to 70 Years

Inclusion criteria

Inclusion criteria: Knee pain on last six months. Pain scale (VAS) should be higher than 4 out of 10. OA patients will have Knee varrus deformity, knee crepitus, and significant limited ROM. Graded 2, and 3 based on Kellgren and Lawrence scale.

Exclusion criteria

Exclusion criteria: Any knee alignment corrective surgery Candidate for joint replacement surgery Any severe change in patient's gait due to pain and limited ROM ligament instability (Grade 3) The involvement of the patellofemoral joint or the lateral femoral condyle is greater than the medial condyle (diagnosed by X-ray) Any disorders that limit daily movements and activities Corticosteroids usage for the knee pain in the last three months Use assistive devices such as knee orthoses and walker Patients with varrus deformity (grade 1, and 3) Cognitive problems diagnosed using EMMSE questionnaire Spinal stenosis, and lumbar disc herniation

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: At the time of referral - after 12 sessions of treatment - one month after treatment. Method of measurement: visual analog scale.;Disability. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: Based on the KOOS questionnaire.;Disability. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: Tegner activity scale questionnaire.;Quality of life. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: OAKHQOL questionnaire.	—

Measure

Time frame

Pain. Timepoint: At the time of referral - after 12 sessions of treatment - one month after treatment. Method of measurement: visual analog scale.;Disability. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: Based on the KOOS questionnaire.;Disability. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: Tegner activity scale questionnaire.;Quality of life. Timepoint: Pre-treatment, Immediately after completion of treatment - one month after completion of treatment. Method of measurement: OAKHQOL questionnaire.

—

Secondary

Measure	Time frame
Foot loading pattern (medial-to-lateral COP index(MLCOPi)). Timepoint: At the time of referral - after 12 sessions of treatment. Method of measurement: Using a foot scan device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHamed Mamipour Gharanjick

Mashhad University of Medical Sciences

hamed.mamipour72@gmail.com+98 51 3869 8719

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026