Crataegus effect on patients undergoing coronary artery bypass surgery

Effects of Crataegus on cardiovascular parameters of patients undergoing coronary artery bypass graft

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016122025772N5

Enrollment

Registered

2017-02-12

Start date

2016-03-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery bypass graft. Mechanical complication of coronary artery bypass and valve grafts

Interventions

Intervention 1: Intervention group: on the third-day after surgery 30 drops of crataegus, three times a day for one month daily. Intervention 2: Control group: on the third day after surgery 30 drops

Treatment - Drugs

Intervention group: on the third-day after surgery 30 drops of crataegus, three times a day for one month daily.

Control group: on the third day after surgery 30 drops of placebo three times a day for one month daily.

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: LVEF less than 30%; The minimum age of 40 and maximum age 80 years; techniques Off-pump coronary artery bypass grafting is a method. Exclusion criteria: require any further surgery; comorbidity to valvular disease such as kidney, liver, diabetes and COPD; The risk of serious mental illness; alcohol and drug addiction; BMI> ...

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Blood pressure. Timepoint: Before intervention,One month after intervention. Method of measurement: Mm Mercury.;Left ventricular ejection fraction. Timepoint: Before intervention, one month after intervention. Method of measurement: Percent.;Exercise tolerance test. Timepoint: Before intervention, one month after intervention. Method of measurement: Minutes.;Malondialdehyde. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;C-reactive protein. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Total cholestrol. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;LDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;VLDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;HDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Mill igrams per deciliter.;Triglyceride. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Fasting blood sugar. Timepoint: Before intervention,One month after intervention. Method of measurement: Milli grams per deciliter.;ALT. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;AST. Timepoint: Before intervention, one month after intervention. Method of measurement: Per liter.;Urea. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Creatinine. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Sodium. Timepoint: Before intervention, one month after intervention. Method of measurement: mEq.;Potassium. Timepoint: Before intervention,One month after intervention. Method	—

Measure

Time frame

Blood pressure. Timepoint: Before intervention,One month after intervention. Method of measurement: Mm Mercury.;Left ventricular ejection fraction. Timepoint: Before intervention, one month after intervention. Method of measurement: Percent.;Exercise tolerance test. Timepoint: Before intervention, one month after intervention. Method of measurement: Minutes.;Malondialdehyde. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;C-reactive protein. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Total cholestrol. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;LDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;VLDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;HDL. Timepoint: Before intervention, one month after intervention. Method of measurement: Mill igrams per deciliter.;Triglyceride. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Fasting blood sugar. Timepoint: Before intervention,One month after intervention. Method of measurement: Milli grams per deciliter.;ALT. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;AST. Timepoint: Before intervention, one month after intervention. Method of measurement: Per liter.;Urea. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Creatinine. Timepoint: Before intervention, one month after intervention. Method of measurement: Milli grams per deciliter.;Sodium. Timepoint: Before intervention, one month after intervention. Method of measurement: mEq.;Potassium. Timepoint: Before intervention,One month after intervention. Method

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyyed Abbas Zojaji

Exir Teb Zakaria Company

exirtebzakaria@gmail.com+98 51 3502 4824

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026