pulmonary fibrosis. Other interstitial pulmonary diseases with fibrosis
Conditions
Interventions
Participants will get a daily supplement of vitamin E with 200 IU dosage, vitamin C supplement with 250 mg dose every other day and 50000 IU of vitamin D once a week and for 8 weeks and another one in
Treatment - Drugs
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Adults (20 years<) with idiopathic pulmonary fibrosis and according to the guidelines of Thoracic Society United States of America and Respiratory Health Association of Europe and final confirmation of respiratory disease physician, patients diagnosed for more than 6 months; Both sex; Avoiding the use of vitamin supplements Exclusion criteria: Unwillingness of individuals to continue participating in the study; Admission supplement inadequate (less than 80% of supplements)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percent of Forced Exspiratory Volume in First Second FEV1. Timepoint: before intervention and 3 month after starting the intervention. Method of measurement: spirometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Transforming growth factor ß1. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Inspiratory Reserve volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Expiratory Reserve Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Protein carbonyls. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Residual Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;Tidal Volume. Timepoint: Before intervention and 3 month after intervention. Method of measurement: spirometry.;High-sensitivity c-reactive protein. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit.;Erythrocyte sedimentation rate. Timepoint: Before intervention and 3 month after intervention. Method of measurement: measurement kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadreza Vafa
Iran University of Medical Sciences
Outcome results
None listed