Comparison of two treatments for improving the outcomes in awake intubation

Comparison of the quality of awake intubation with fiber optics in patients receiving dexmedetomidine with midazolam and fentanyl in Rasoul-e-Akram Hospital in 2016-17

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161220031487N9

Enrollment

Registered

2018-04-27

Start date

2017-12-21

Completion date

Unknown

Last updated

2018-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Failed or difficult intubation. Failed or difficult intubation

Interventions

Intervention 1: Intervention group: infusions of 1mcg / kg of trimodimide dosage in 10 minutes and then continued at 0.5 mcg / kg / h. Intervention 2: Control group: 2 mcg / kg fentanyl and 1 mg mida

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age range 20 to 60 years ASA grade 1-2 Candidate for elective surgical operation in Rasoule-Akram hospital Candidate for awake intubation

Exclusion criteria

Exclusion criteria: Pregnant women Patients not able to collaborate (intellectual disability, low awareness, ...) Patients with A-V block in ECG Patients addicted to drugs of abuse or analgesics History of allergic reaction to each of the drugs under study Emergency operation Heart failure Uncontrolled asthma Incidence of adverse effects during study (including laryngospasms, bronchospasm, Ramsey scale >4 , any kind of hemodynamic changes requiring pharmaceutical intervention)

Design outcomes

Primary

Measure	Time frame
Heart rate. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Blood pressure. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Arterial blood gas analysis. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Arterial blood gas analysis system.;Analgesia. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Ramsey sedation scale.	—

Measure

Time frame

Heart rate. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Blood pressure. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Using patient monitoring system.;Arterial blood gas analysis. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Arterial blood gas analysis system.;Analgesia. Timepoint: Before premedication, after premedication and after intubation. Method of measurement: Ramsey sedation scale.

—

Secondary

Measure	Time frame
Attempts for awake intubation with fiber optic. Timepoint: During intubation. Method of measurement: Counting the number of attempts for intubation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactValiollah Hassani

Iran University of Medical Sciences

valiollah_hassani@yahoo.com+98 982166515001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026