Condition 1: sedation effect of drug regimen in gasterointetinal endoscopy. Condition 2: sedation effect of drug regimen in gasterointetinal endoscopy. Condition 3: sedation effect of drug regimen in gasterointetinal endoscopy. Condition 4: sedation effect of drug regimen in gasterointetinal endoscopy. Condition 5: sedation effect of drug regimen in gasterointetinal endoscopy. Abdominal and pelvic pain Nausea and vomiting Heartburn Dysphagia Other symptoms and signs involving the digestive
Conditions
Interventions
Intervention 1: In MP group oral midazolam half-mg dose and a maximum of 20 milligrams per kilogram of body weight. Intervention 2: Patients in the MP group injected with Propofol (Dayateb co.IRof Ira
Treatment - Other
In MP group oral midazolam half-mg dose and a maximum of 20 milligrams per kilogram of body weight
Patients in the MP group injected with Propofol (Dayateb co.IRof Iran Manufactured by Claris) bolus dose2 mg / kg (children younger than 3 years) and 1 mg / kg (in children older than 3 years) are to
MK Group IV sedation with ketamine in slow (Trittan / Germany) bolus1-2 mg / kg starts and after about 15-10 minutes the effect of ketamine sedation was reduced by as much as 0/5-1 mg / kg in during
In MK group oral midazolam half-mg dose and a maximum of 20 milligrams per kilogram of body weight
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria:1-14 years old childs with gasterointestinal disease ; children with grade I, II classification (American Society of Anesthesia) ASA Exclusion Criteria: chronic diseases such as cardio-pulmonary disease, diabetes, infectious diseases and oncology ; chronic use of drugs affecting the respiratory system and cardiovascular, CNS
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Check the heart rate after administration of oral midazolam and ketamine and propofol sedative drugs. Timepoint: 1)Two minutes after administration of oral midazolam 2) When entering the endoscope 3) five minutes after endoscopic. Method of measurement: vital sign monitoring machine(saadat,BS-SN SNTI/e2/m/c).;Check the Respiratory Rate after administration of oral midazolam and ketamine and propofol sedative drugs. Timepoint: 1)Two minutes after administration of oral midazolam 2) When entering the endoscope 3) five minutes after endoscopic. Method of measurement: vital sign monitoring machine(saadat,BS-SN SNTI/e2/m/c).;The possible need to add a dose of medication ine MP groups as inadequate sedation with commonly defined doses. Timepoint: during endoscopy if inadequate sedation. Method of measurement: The milligrams of the drug.;The sedative affect in both groups before and during endoscopy start. Timepoint: Begins immediately before and five minutes after the start of endoscopy. Method of measurement: Rasey score clasification( 5=RSS ).;Check the Mean Arterial Pressure after administration of oral midazolam and ketamine and propofol sedative drugs. Timepoint: 1)Two minutes after administration of oral midazolam 2) When entering the endoscope 3) five minutes after endoscopic. Method of measurement: vital sign monitoring machine(saadat,BS-SN SNTI/e2/m/c).;Check the arterial O2 saturation after administration of oral midazolam and ketamine and propofol sedative drugs. Timepoint: 1)Two minutes after administration of oral midazolam 2) When entering the endoscope 3) five minutes after endoscopic. Method of measurement: vital sign monitoring machine(saadat,BS-SN SNTI/e2/m/c).;The possible need to add a dose of medication ine MK groups as inadequate sedation with commonly defined doses. Timepoint: during endoscopy if inadequate sedation. Method of measurement: The milligrams of the drug. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare vital signs after endoscopy. Timepoint: Fifteen minutes after the completion of endoscopy. Method of measurement: vital sign monitorin mashine(saadat).;The endoscopist satisfaction of sedation effect of each drug regimen. Timepoint: After the endoscopy. Method of measurement: Skills and experience of the endoscopist.;Compare potential drug side effects in both groups. Timepoint: After drug administration, during endoscopy,finish endoscop?. Method of measurement: Phisical exam and History.;Compare of recavery score. Timepoint: Fifteen minutes after the completion of endoscopy. Method of measurement: steward score system. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Mahdi Farhadi
Amirkola Childeren's Hospital
Outcome results
None listed