Comparison of the effect of 40% autologous serum drop with artificial tear drop in improving corneal epithelial injury after corneal collagen cross-linking surgery,

Comparison of the effect of 40% autologous serum drop with artificial tear drop in improving corneal epithelial injury after corneal collagen cross-linking surgery, epithelium-off: a double-blind randomized controlled trial).

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161218031450N6

Enrollment

Registered

2023-10-29

Start date

2023-09-09

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus.

Interventions

Intervention group:.

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients with bilateral keratoconus ready for surgery, none of whose eyes have been cross-linked before. Consent to participate in the study Patients with keratoconus in both eyes

Exclusion criteria

Exclusion criteria: Patients with a corneal thickness less than 400 microns history of ocular herpes recent history of any type of eye infection presence of corneal scarring or opacity neurotrophic keratopathy positive history of autoimmune diseases Pregnancy

Design outcomes

Primary

Measure	Time frame
Corneal epithelium closure. Timepoint: 1,2,3 post op days. Method of measurement: with slit lamp.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mostafaei

Tabriz University of Medical Sciences

alimostafaie@yahoo.com+98 41 3657 7330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026