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Comparison of outcomes of subtenon Mitomycin C injection Versus soaked sponges mitomycin C application in Deep Sclerectomy.

Comparison of outcomes of subtenon Mitomycin C injection Versus soaked sponges mitomycin C application in Deep Sclerectomy in patients with primery open angle glaucoma and psudoexfoliation glaucoma.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20161218031450N5
Enrollment
40
Registered
2021-08-16
Start date
2021-07-11
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open Angle Glaucoma. Open-angle glaucoma

Interventions

Intervention 1: Intervention group: In this method, first subthenon injection of 0.1 ml of mitomycin C 0.2 mg / ml is performed and after conjugate massage, the flap is removed. Continuation of the su

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with open-angle glaucoma (OAG) with advanced caping and progressive visual field defects A patient with open-angle glaucoma (OAG) who needs medication to control IOP but does not tolerate medication Patients with open-angle glaucoma (OAG) whose IOP is not well controlled despite medication. Patients with open-angle glaucoma (OAG) who need multiple medications to control IOP Willingness to participate in the study (patients with informed consent)

Exclusion criteria

Exclusion criteria: Lack of proper access to the patient for long-term follow-up Patients with any congenital abnormality of the anterior chamber angle Patients with ocular infections Patients with a history of ocular surgery Patients with uveitis Patients with corneal diseases that can affect IOP or measure it (corneal opacity, large pterygium, etc.). Patients with diabetes and hypertension Patients with neovascular glaucoma In case of any ocular or systemic complications, patients are excluded from the study

Design outcomes

Primary

MeasureTime frame
Intraocular pressure. Timepoint: Before surgery (one day, 2 weeks, 1 month, 2 months, 3 months, 6 months, after surgery). Method of measurement: Using a Goldman tonometer.

Secondary

MeasureTime frame
Bleb apperance. Timepoint: 2 months, 3 months, 6 months after surgery. Method of measurement: IBAG(indiana Bleb Grading Scale).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Mostafaei

Tabriz University of Medical Sciences

alimostafaie@yahoo.com+98 41 3657 7330

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026