Acute anal fissure. Acute anal fissure
Conditions
Interventions
Intervention 1: Patients with acute anal fissure in positive control group with conventional medication. which is administered as a rectal ointment for two weeks, twice a day, each time a tip of the
Treatment - Drugs
Patients with acute anal fissure in positive control group with conventional medication. which is administered as a rectal ointment for two weeks, twice a day, each time a tip of the finger (0.5 g)
Patients with acute anal fissure in traditional drug group (cerate supplies of rose oil and wallflower oil and beeswax) which is administered as a rectal ointment for two weeks, twice a day, each time
Patients with acute anal fissure in placebo group: a simple cerate base (cerate of sesame oil and wax) which is administered as a rectal ointment for two weeks, twice a day, each time a tip of the fin
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: The expert diagnosis af anal fissure; willingness of patient to cooperate in the project; age of 20-50 years; lack of sensitivity to drug ingredients. Exclusion criteria: Crohn's disease; fistula in the anal area; anal cancer; cardiovascular disorders; hemorrhoids; pregnancy and lactation; patients who consume blood pressure drugs; calcium channel blockers or nitrates; patients with a history of chronic headache; renal failure; HIV; tuberculosis; taking drugs such as heparin or aspirin and certain diseases such as thyroid problems.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Local wound healing. Timepoint: Before taking the drug, after a time period of two weeks and 4-6 weeks after drug is used. Method of measurement: visual scales of wounds.;Pain relief. Timepoint: Before taking the drug, after a time period of two weeks and 4-6 weeks after drug is used. Method of measurement: Quastionary of pain score. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improve quality of life. Timepoint: During and after the course of treatment. Method of measurement: quality of life questionnaire.;Internal anal sphincter pressure. Timepoint: after the consumption of cerate. Method of measurement: manometry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGhazaleh Mosleh
Faculty of pharmacy
Outcome results
None listed