Bipolar Mood Disorder, current episode manic without psychotic feauters. The patient is currently manic, without psychotic symptoms (as in F30.1), and has had at least one other affective episode (hypomanic, manic, depressive, or mixed) in the past.
Conditions
Interventions
Intervention 1: Intervention group: Aripiprazole is administered at a dose of 10 mg per day for 6 weeks. Intervention 2: Control group: Placebo in terms of shape, size and weight similar to the ?Aripi
Treatment - Drugs
Placebo
Intervention group: Aripiprazole is administered at a dose of 10 mg per day for 6 weeks
Control group: Placebo in terms of shape, size and weight similar to the ?Aripiprazole drug for 6 weeks
Sponsors
Vice chancellor for research, Tabriz University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: The definitive diagnosis of bipolar I disorder according to DSM-IV-TR criteria; being in the partial or complete recovery phase based on Yang Mania Rating Scale; having the necessary criteria for diagnosis of nicotine dependence according to DSM-IV-TR criteria; age 18-60 Years old; male gender and consent to attend the study through the signing of informed consent. ?Exclusion Criteria: history of any allergic reaction to drug disorder with respect to Aripiprazole or other anti psychotics; dependence on other substances (based on the patient's history and the outcome of the test of morphine and methamphetamine at the start of the intervention); the use of other drugs used to quit nicotine; Use of medications other than bipolar disorder; history of physical illness (liver failure, renal failure); history of mental retardation; occurrence of any side effects due to Aripiprazole; history of cognitive impairment (dementia).
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Smoking rate (nicotine). Timepoint: before intervention,Six weeks after the intervention. Method of measurement: Fagerstrom Test for Nicotine Dependence (FTQ). | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects of Aripiperazole. Timepoint: First and Fourth Week of Intervention. Method of measurement: Glasgow Antipsychotic Side-effect Scale (GASS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDR Mohammad Taher Taieb Zadegan
Razi Hospital
Outcome results
None listed