knee osteoarthritis. Primary gonarthrosis
Conditions
Interventions
Intervention 1: intervention Group: local production red clover twice a day, each time 10 drops (containing 40 mg isoflavones) and routine treatment with meloxicam tablets. Intervention 2: Control: ol
Treatment - Drugs
intervention Group: local production red clover twice a day, each time 10 drops (containing 40 mg isoflavones) and routine treatment with meloxicam tablets
Control: olive oil 10 drops twice a day and routine treatment with meloxicam tablet
Sponsors
Research and Technology Vice-Chancellory of Mashhad University of Medical Science
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for this study include the following: Initial symptomatic osteoarthritis in at least one knee by clinical or radiological criteria ACR (American College of Rheumatology) is approved; a score higher than 40 at baseline VAS scale; Obtain routine medical treatment (meloxicam tablets) for at least two weeks before the study; aged between 60 and 80 years Exclusion criteria are as follows: The patient dissatisfaction cooperation during the study; The need for new therapeutic intervention during the study period; skin disease or ulcer at the site of drug; effects (local or systemic probable) by treatments performed during the study; active liver disease or renal malignancies; Secondary osteoarthritis or suspected; patients treated with hormonal drugs; anticoagulation therapy; Patients with a history of ischemic or hemorrhagic stroke; patients with a history of deep vein thrombosis; The 4-week treatment with oral corticosteroids at baseline; The intra-articular injection of hyaluronic acid in the three months before the start of the study; BMI> 37kg / m2; clinically obvious swelling of the knee joint disease (stroke test> trace)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: Early intervention, two weeks after the intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: Womac questionnaire and vas scale.;Joint stiffness. Timepoint: Early intervention, two weeks after the intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: Womac questionnaire.;Physical performance. Timepoint: Early intervention, two weeks after the intervention, four weeks after the intervention, eight weeks after intervention. Method of measurement: Womac questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMasoud Mokhtari
Faculty of Iranian Traditional Medicine and Complementary of Mashhad University of Medical Sciences
Outcome results
None listed