Effect of intraperitoneal irrigation with sodium bicarbonate versus normal saline on post-operative pain in patients who are candidate for elective laparotomy

Effect of intraperitoneal irrigation with sodium bicarbonate versus normal saline on post-operative pain in patients who are candidate for elective laparotomy: a double blind randomized clinical trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT201612089014N138

Enrollment

Registered

2016-12-09

Start date

2016-05-04

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparotomy. Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

Interventions

Intervention 1: Intervention group: Intraperitoneal irrigation with sodium bicarbonate plus normal saline for 2 to 5 minutes during surgery. Intervention 2: Control group: Intraperitoneal irrigation w

Treatment - Drugs

Intervention group: Intraperitoneal irrigation with sodium bicarbonate plus normal saline for 2 to 5 minutes during surgery.

Control group: Intraperitoneal irrigation with normal saline for 2 to 5 minutes during surgery.

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: age between 18 to 65 years old; candidate for elective laparotomy. Exclusion criteria: loss of consciousness; heart failure; hemodynamic disorder; renal and hepatic and lung diseases; electrolyte imbalance.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain at surgery site. Timepoint: 12 and 24 hours post-operation. Method of measurement: using VAS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Roohollah Hoseini

Besat Hospital

Drhosseini81@gmail.com+98 81 3364 0030

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026