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Effect of Nicorandil on Reducing Angioplasty Damage to Myocardium in Patients with Stable Angina Pectoris Undergoing Elective Angioplasty

Effect of Nicorandil on QT Dispersion in Patients with Stable Angina Pectoris Undergoing Elective Angioplasty

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016120731159N1
Enrollment
90
Registered
2017-04-28
Start date
2014-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Ischemic Heart Disease. Chronic ischaemic heart disease, unspecified

Interventions

Intervention 1: The Intervention Group Received A Total Of 60 Mg Of Nicorandil 20 Mg Tablets (Merck, USA) Orally In 3 Intervals
First Turn: 12 Hours Before Angiography, Second Turn: 3 Hours Before Angiography, And The Last Turn: 6 Hours After Angioplasty. The Patients Merely Underwent Angiography With No Need For Angioplasty W
Treatment - Drugs
The Intervention Group Received A Total Of 60 Mg Of Nicorandil 20 Mg Tablets (Merck, USA) Orally In 3 Intervals
The Control Group Received Isoshape, Isocolor And Isosmall Tablets (Merck, USA) Orally In 3 Intervals

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Inclusion Criteria: Chronic Stable Ischemic Heart Disease Which Were Candidated For Angiography And Probably Angioplasty Exclusion Criteria Included: History Of Heart Surgery; Having Branch Block With Qrs > 120 Miliseconds Or Complete Atrioventricular Block In ECG; Atrial Fibrillation; Renal Failure Or Electrolyte Abnormalities; Use Of Narcotics; No Need To Perform Angioplasty And Complications During Angioplasty (Acute Stent Thrombosis, Coronary Dissection, Adjacent Vessels Lost And No Reflow Of The Arteries).

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Difference In QTC Dispersion. Timepoint: 12 Hours Before And After Angioplasty. Method of measurement: By ECG IN Milliseconds.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNima Nakhaee

Mashad University of Medical Sciences

nakhaeen921@mums.ac.ir; nakhaeenima@gmail.com+98 52 3767 0787

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026