chemotherapy induced oral mucositis( stomatitis). Oral mucositis (ulcerative) due to antineoplastic therapy
Conditions
Interventions
Intervention 1: Gabapentine mouthwash (5 percent) ,7.5 ml ,three times a day for 2 weeks. Intervention 2: Placebo mouthwash ,7.5 ml, 3 times a day for 2 weeks.
Treatment - Drugs
Placebo
Gabapentine mouthwash (5 percent) ,7.5 ml ,three times a day for 2 weeks
Placebo mouthwash ,7.5 ml, 3 times a day for 2 weeks
Sponsors
Vice chancellor for research, Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:cancer patients receiving chemotherapy regimens containing 5_fluorouracil , anthracyclines or high dose of methotrexate Exclusion criteria: Gabapentine intolerance , inappropriate use of the mouth wash or oral use of Gabapentine
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: After 1 week of intervention. Method of measurement: Quastionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Dysphagia to liquids. Timepoint: Before and after 2 weeks of intervention. Method of measurement: Ask a question.;Dysphagia to solids. Timepoint: Before and after 2 weeks of intervention. Method of measurement: Ask a question. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda Zamani
Vice chancellor for research, Mazandaran University of Medical Sciences
Outcome results
None listed