Efficacy and safety evaluation of the cream including Citystem extract and Phytessence extract on reducing skin damage caused by air pollution

Efficacy and safety evaluation of the cream including Citystem extract derived from Marrubium vulgare plant and Phytessence extract derived from Phytessence peach flower on reducing skin damage caused by air pollution

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161207031288N14

Enrollment

Registered

2022-11-26

Start date

2022-11-21

Completion date

Unknown

Last updated

2023-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skin damage caused by air pollution.

Interventions

Intervention 1: Intervention group:Using twice a day (morning and night) the cream containing Citystem extract derived from Marrubium vulgare plant and Phytessence extract derived from Phytessence pea

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Signing the infirmed consent form and agree to regularly attend follow-up courses 18 -50 years old men and women Exposure to the outside air (at least one hour in a day)

Exclusion criteria

Exclusion criteria: People with any kind of skin disease Suffering from a chronic disease affecting the skin condition (diabetes, thyroid diseases,...) Smoking Pregnancy or lactation

Design outcomes

Secondary

Measure	Time frame
Skin PH. Timepoint: Before the study, 4 and 8 weeks after the intervention. Method of measurement: MPA 580(Multi Probe Adaptor) device.;Skin erythema. Timepoint: Before the study, 4 and 8 weeks after the intervention. Method of measurement: MPA 580(Multi Probe Adaptor) device.	—

Primary

Measure	Time frame
Trance epidermal water lost (TEWL). Timepoint: Before the study, 4 and 8 weeks after the intervention. Method of measurement: MPA 580(Multi Probe Adaptor) device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSaman Ahmad Nasrollahi

Tehran University of Medical Sciences

samannasrol@gmail.com+98 21 8897 2220

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026