periorbital wrinkle, dark circle and puffiness.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male or female aged 30-60 years The presence of periorbital wrinkle, dark circle and puffiness Signed informed consent knowingly
Exclusion criteria
Exclusion criteria: Critical untreated systemic disease in medical history Any facial rejuvenation treatment, including treatment with topical or oral products or supplements during the last four weeks Any facial rejuvenation treatment including rejuvenation devices or surgical procedures and Botox injections during the last four months Sensitivity and allergy to the components of the formulation Use of any eye cream or eye sunscreen cream during the last four weeks Use of anti-wrinkle or brightening cleansers over the past four weeks Pregnancy or lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Area, volume and depth of periorbital wrinkle. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Visioface. | — |
Secondary
| Measure | Time frame |
|---|---|
| Periorbital wrinkle, dark circle and puffiness. Timepoint: Before intervention and 4 and 8 weeks after treatment. Method of measurement: Two independent dermatologists perform evaluation and scoring with the help of right and left lateral view and full face photos by Visioface, based on the percentage of improvement in periorbital puffiness using scale 0 to 3 (0 = no improvement 1 = relative improvement 2 = good improvement 3 = Excellent improvement) . | — |
Countries
Iran (Islamic Republic of)
Contacts
Tehran University of Medical Sciences