Allergic Rhinitis. Allergic rhinitis due to pollen
Conditions
Interventions
3 intralymphatic inguinal injections under the guide of sonography( 1000 SQ-U Salsola-pollen extract within 4 weeks interval)..
Sponsors
Vice chancellor for research, Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with Seasonal or Perennial Allergic Rhinitis Aggravated symptoms from mid Summer till mid Autumn for at least two years Age :15-65 years Positive Skin Prick Test response to Salsola Kali Symptoms remain troublesome despite treatment The ability to comply with study procedures
Exclusion criteria
Exclusion criteria: Past history of Autoimmune Diseases Ongoing Systemic Immunosuppressive treatment. The presence of Pregnancy The presence of Immunodeficiency The presence of Allergic Asthma The presence of Heart Diseases Ongoing Beta Blocker or ACE inhibitors drug usage The presence of Malignancy The presence of any chronic diseases Current symptoms of Upper Respiratory Tract Infection History of life-threatening Anaphylaxis or Angioedema
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Symptoms, Drug Usage, Skin Prick Test, Specific IgE. Timepoint: Befor The Trial. Method of measurement: Sign And Symptoms, Antiasthmatic Drugs Usage, Skin Prick Test, Peakflowmetry and Specific IgE. | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical symptoms, drug usage, specific IgE. Timepoint: One month after end of treatment. Method of measurement: Physical examination and peakflowmetry. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNasrin Sadat Motevalli Haghi
Mashhad Unevesity of Medical Science
Outcome results
None listed