menopausal symptoms. Symptoms such as flushing, sleeplessness, headache, lack of concentration, associated with menopause
Conditions
Interventions
Intervention 1: First group will be given fennel extract, 2 times daily for 8 weeks. Intervention 2: Second group will be given placebo, 2 time daily for 8 weeks.
Treatment - Drugs
First group will be given fennel extract, 2 times daily for 8 weeks.
Second group will be given placebo, 2 time daily for 8 weeks.
Sponsors
Vice chancellor for research, Kermanshah University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: the women ranging from 45 to 65 years old; menstrual period is elapsed minimally one year and maximally three years; the number of their hot flushes is at least 2 times a day. Exclusion criteria: smoking; undergoing hormone; antibiotics therapy for a period of 3 months at least; systemic diseases such as kidney disease; blood pressure; diabetes; blood fat; depression and anxiety (anxiety and depression diagnosis based on diagnostic criteria DSM5 by psychiatrist); taking anti-thyroid drugs; gabapentin; SSRI; sulfonamides; methotrexate; Tryamtryn; sulfasalazine; estrogen; uptake of traditional medicines such as drug-induced flushing.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vasomotor. Timepoint: before intervention-2 weeks later- 4 weeks later- 8 weeks later. Method of measurement: Green questionnaire.;Depression. Timepoint: before intervention-2 weeks later- 4 weeks later- 8 weeks later. Method of measurement: Green questionnaire.;Sexual Function. Timepoint: before intervention-2 weeks later- 4 weeks later- 8 weeks later. Method of measurement: Green questionnaire.;Anxiety. Timepoint: before intervention-2 weeks later- 4 weeks later- 8 weeks later. Method of measurement: Green questionnaire. | — |
Countries
Iran (Islamic Republic of)
Outcome results
None listed