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The effect of ursodeoxycholic acid for treatment of large and multiple common bile duct stones

The effect of adding ursodeoxycholic acid to common bile duct (CBD) stenting for treatment of large and multiple CBD stones

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20161205031252N8
Enrollment
64
Registered
2018-08-29
Start date
2018-09-06
Completion date
Unknown
Last updated
2018-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CBD stones. Calculus of gallbladder with acute cholecystitis

Interventions

Intervention 1: Intervention group: Common bile duct stenting with Ursodeoxycholic Acid capsule, KoushanPharmed company, 300 mg, oral, once daily, for two months. Intervention 2: Control group: Common

Sponsors

Ghoum University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Common bile duct stone with a diameter greater than 15 mm More than 3 stones in common bile duct

Exclusion criteria

Exclusion criteria: History of recent surgery on bile ducts History of gasterectomy History of duodenal stricture Patients who do not fill the informed concept form

Design outcomes

Primary

MeasureTime frame
Common bile duct clearing. Timepoint: 2 months after CBD stenting. Method of measurement: By endoscopic retrograde cholangiopancreatography.

Secondary

MeasureTime frame
Chollangitis. Timepoint: After endoscopic retrograde cholangiopancreatography. Method of measurement: According to Charcot's triad including abdominal pain, serum bilirubin measurement and core body temperature measurement.;Pancreatitis. Timepoint: After endoscopic retrograde cholangiopancreatography. Method of measurement: Serum amylase level measurement.;Reduction in stones size. Timepoint: Two months after common bile duct stenting. Method of measurement: By fluoroscopy during endoscopic retrograde cholangiopancreatography.;Reduction in common bile duct (CBD) stone number. Timepoint: Two months after CBD stenting. Method of measurement: By endoscopic retrograde cholangiopancreatography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAhmad Hormati

Ghoum University of Medical Sciences

hormatia@muq.ac.ir+98 25 3612 2053

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 25, 2026