acne vulgaris. Acne vulgaris
Conditions
Interventions
Intervention group: systemic isotertinoein(oral),0.5 mg/kg,daily,for 3 months.
Treatment - Drugs
Intervention group: systemic isotertinoein(oral),0.5 mg/kg,daily,for 3 months
Sponsors
Vice Chancellor for Research of Mazandaran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
13 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1. Patients with moderate to severe acne candidates for systemic isotretinoin therapy.;consent to participate in the study Exclusion criteria: Patients who are pregnant or lactating women;topical or systemic anti-acne drugs or antibiotics were used a month prior to or in conjunction with study.; Patients have been affected with infectious and respiratory diseases a month before o during the study.; Patients with chronic liver disease or peptic ulcer 5-consumers of drugs that cause acne include: vitamin B12, topical steroids or systemic anti-TB drugs, lithium, azathioprine, carbamazepine and phenytoin;patients with Hematologic disorders (according hematologic side effects of treatment)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nose and throat microbial flora. Timepoint: before treatment intervention & 3 months after treatment intervention. Method of measurement: Laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| -. Timepoint: -. Method of measurement: -. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactGhasem Rahmatpour Rokni
Mazandaran University of Medical Sciences
Outcome results
None listed