The efficacy of cognitive training intervention on cognitive functions of the older adults with mild cognitive impairment

The effects of attention and working memory-based cognitive intervention on behavioral and neurological evidences of cognitive functions in older adults with mild cognitive impairment

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20161204031227N1

Enrollment

Registered

2021-08-09

Start date

2017-09-05

Completion date

Unknown

Last updated

2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment. Mild cognitive impairment, so stated

Interventions

Intervention 1: Intervention group: In the Intervention group, After the evaluation session (using cognitive function evaluation tests) and recording of Event-Related Potentials (ERPs) participants w

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: Monolingual Persian-speaking elderly people over 60 years old with education higher than elementary level Memory complaint by the patient or a close relative Objective Memory impairment in Rey Auditory Verbal Learning Test (1.5 SDs below the age-matched and education-matched norms) Independence in activities of daily living and complex activities of life Normal global cognitive function (Mini-Mental Status Examination score > 22 ) No evidence of dementia No depression (Geriatric Depression Scale score < 5)

Exclusion criteria

Exclusion criteria: History of a variety of neurological, medical and psychiatric disease including a history of stroke in the last 12 months, cardiovascular disease, schizophrenia, personality disorder, and bipolar disorder History of substance abuse Unmodified sensory impairment and hand mobility impairment History of participating in cognitive intervention programs in the last 6 months

Design outcomes

Primary

Measure	Time frame
Selective attention. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: Attention Network Test (ANT).;Working memory. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: N-back test.;Amplitude of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Latency of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Amplitude of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Latency of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.	—

Measure

Time frame

Selective attention. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: Attention Network Test (ANT).;Working memory. Timepoint: Before intervention, immediately after 12 sessions of intervention and 3 months later. Method of measurement: N-back test.;Amplitude of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Latency of N100 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Amplitude of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.;Latency of P300 component of event-related potentials. Timepoint: Before intervention and immediately after 12 sessions of intervention. Method of measurement: Event-related potentials were recorded using Mitsar amplifier from 32 scalp electrodes during the attention network test.

—

Secondary

Measure	Time frame
Episodic memory score. Timepoint: Before intervention, Immediately after 12 sessions of intervention and 3 months later. Method of measurement: Rey Auditory Verbal Learning Test (RAVLT).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdieh Esmaeili Tarzi

University of social welfare and rehabilitation sciences

mah.esmaeili@uswr.ac.ir+98 21 8876 1695

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026