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Comparison effect of Acetaminophen and Fentanyl on the pain reduction during and after Trans Urethral Lithotripsy surgery

Comparison effect of intravenous Acetaminophen and Fentanyl as a premedicant for intra-operative and post-operative pain reduction in Trans Urethral Lithotripsy surgery.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT2016120331215N1
Enrollment
80
Registered
2017-07-26
Start date
2017-05-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trans Urethral Lithotripsy. Ureteric stone

Interventions

Intervention 1: Intervention group: Receiving 15 mg/kg intervenes Acetaminophen diluted with Normal saline to volume of 100 ml before surgery. Receiving 1.5 micro gr/ kg intervenes Fentanyl intra-oper
Treatment - Drugs
Placebo
Intervention group: Receiving 15 mg/kg intervenes Acetaminophen diluted with Normal saline to volume of 100 ml before surgery. Receiving 1.5 micro gr/ kg intervenes Fentanyl intra-operation.
Control group: Receiving 100 ml Normal saline before surgery. Receiving 2 ml Normal saline intra-operation.

Sponsors

Vice chancellor of Reseach, Qazvin University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age of 18 years and more; patients in class of I and II based on ASA; patients at risk for surgery. Exclusion criteria: History of liver disease; History of allergic reactions or intolerance to the studied drugs; Narcotic addiction; ASA class of III and more; History of narcotic taking before surgery; keratinin more than 1.5 mg/dl; Insulin-dependent diabetes; History of taking antidepressants or anticonvulsants; History of Gastroesophageal reflux and Hernia Hyatal; Body Mass Index=35; Pregnancy; Alzheimer's disease or mental retardation.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain severity. Timepoint: Intra-operative and post-operative in recovery and 24 hours postoperative in surgery ward. Method of measurement: intra-operative with controlling blood pressure change and hurt rate more than 20% baseline and visual analogue scale (VAS).

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fatemeh Hosseini Fard

Qazvin University of Medical Scinces

Aramack@gmail.com+98 28 3333 5800

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026