A comparision of magnesium sulfate and Phenytoin on eclampsia seizure in pregnant women with preeclampsia and eclampsia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016120311020N7

Enrollment

400

Registered

2016-12-15

Start date

2010-06-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seizures. Eclampsia in the puerperium, Eclampsia in labour

Interventions

Intervention 1: Intervention group 1: 4 gram of magnesium sulfate in 100 cc Ringer ,IV, within 15 to 20 minutes. Then, 2 g in 100 cc serum ringer intravenously injected per hour. Intervention 2: Gro

Treatment - Drugs

Intervention group 1: 4 gram of magnesium sulfate in 100 cc Ringer ,IV, within 15 to 20 minutes. Then, 2 g in 100 cc serum ringer intravenously injected per hour.

Group II: 750 mg of phenytoin in100 cc Ringer intravenously and then table phenytoin 125 mg ,TDS

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: moderate or sever preeclampsia or eclampsia Exclusion criteria: twines pregnancy, history of hypertension or medical disease, history of seizure and neorology problems, smoking and alcohol consumption.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Seizures. Timepoint: During 48 hours after delivery. Method of measurement: Observation.	—

Secondary

Measure	Time frame
Apgar score. Timepoint: 1 minute after delivery. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Khoshideh

Tehran University of Medical Sciences

khooshide@tums.ac.ir+98 21 7771 9922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026