Polycystic Ovarian Syndrome(PCOS). Polycystic Ovarian Syndrome(PCOS)
Conditions
Interventions
Intervention 1: Intervention group: The intervention group consumed 800 mg of garlic tablets daily for 2 months. Intervention 2: The control group consumed 800 mg of placebo daily for 2 months.
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: All women with polycystic ovary syndrome who are at least 18 and up to 45 years old
Exclusion criteria
Exclusion criteria: People who follow a certain diet People who follow a specific exercise program People undergoing any drug treatment such as spironolactone, finasteride, isotretinoin, letrozole, clomiphene, gonadotropins, rosiglitazone, pioglitazone, or surgery such as laparoscopic ovarian surgery and assisted reproductive technology (PCOS) to treat symptoms they do Any serious or significant systemic illness requiring treatment such as cancer, gastrointestinal, hepatic or endocrine disorders, thyroid dysfunction, diabetes mellitus, hyperprolactinemia, cardiovascular disorders, renal disorders, blood coagulation disorders, neurological disorders, Insomnia, Pemphigus Disease, Joint Rheumatism and Non-Related Reproductive Disorders (PCOS) History of pregnancy hypertension Family history of stroke Any of the following: Alcohol, tobacco, anti-estrogens, oral or injectable corticosteroids Pregnancy lactation Menopause Use of anticoagulants such as warfarin and heparin, Taking aspirin History of any allergy, intolerance or harmful drug reaction to garlic and its products Taking garlic pills or supplements containing garlic at least 2 months before the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Antioxidant Capacity (TAC). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Colorimetric method.;Malon Di Aldehyde (MDA). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Colorimetric method.;Lipid profile. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Spectrophotometry.;Fasting blood sugar(FBS). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Spectrophotometry.;Insulin. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: It will be measured by ELISA kit.;Insulin Resistance (HOMA-IR). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Will be measured computationally.;Testosterone hormone. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: It will be measured by ELISA kit.;Glutathione(GSH). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Colorimetric method.;Catalase(CAT). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Colorimetric method.;Sex Hormone Binding Globulin (SHBG). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: It will be measured by ELISA kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: sphygmomanometer.;Weight. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Balance.;Body Mass Index(BMI). Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: Balance and meter.;Waist. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: meter.;Around the abdomen. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: meter.;Hip circumference. Timepoint: Before the intervention and 2 months after the intervention. Method of measurement: meter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Mansour Alavi Naini
Esfahan University of Medical Sciences
Outcome results
None listed