Condition 1: Hearing loss. Condition 2: Sudden hearing loss. Sudden idiopathic hearing loss Sudden idiopathic hearing loss
Conditions
Interventions
Intervention 1: In intervention group, patients receive three intratympanic injections of 2 mg hyaluronic acid +2.4 mg Dexamethasone in combination. Intervention 2: The control group, receive th
Treatment - Drugs
In intervention group, patients receive three intratympanic injections of 2 mg hyaluronic acid +2.4 mg Dexamethasone in combination.
The control group, receive three injections of 2.4 mg Dexamethasone intratympanically.
Sponsors
Vice Chancellor for Research, Isfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria consisted of unilateral hearing loss (occurring within 72 hours), the hearing threshold average greater than 50 dB, symptoms appearance within 7 days from our intervention, patient's pure tone audiogram at frequencies 250 500, 1000, 2000, 4000 and 8000 Hz, age range 18-80 years, lack of acoustic tumor, middle ear diseases, autoimmune diseases, vestibular problem (Menier disease&..), cardiovascular disorders and diabetes, no history of ear surgery and the patient’s consent to participate in the study. Meanwhile patient’s refusal to attend on time for follow up visits, any limitation to inject intra tympanum via external auditory canal such as stenosis, anatomical deformities and external and middle ear infections were considered as exclusion criteria.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hearing threshold in different frequencies. Timepoint: Before & two weeks after intervention. Method of measurement: Pure tone audiometry. | — |
Secondary
| Measure | Time frame |
|---|---|
| Infection. Timepoint: One week after intervention. Method of measurement: Ear examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Amin Kalcoo
Faculty of Medicin
Outcome results
None listed