The effect of topical Cyclosporin in uveitis treatment

Evaluation of clinical effect of topical Prednisolon with and without topical Cyclosporin 2% in the treatment of acute non infectious anterior uveitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT2016112731135N1

Enrollment

Registered

2017-02-12

Start date

2017-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Anterior Uveitis. Acute and subacute iridocyclitis Anterior uveitis Cyclitis Iritis acute, recurrent or subacute

Interventions

Intervention 1: Patients in the intervention group receiving topical Cyclosporin2% four times daily(in addition to the standard treatment of uveitis) until complete remission of inflammation. Interven

Treatment - Drugs

Patients in the intervention group receiving topical Cyclosporin2% four times daily(in addition to the standard treatment of uveitis) until complete remission of inflammation.

Patients in control group receiving artificial tear four times daily( in addition to standard treatment of uveitis) until complete remission of inflammation.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Inclusion criteria: First episode of acute anterior non-infectious uveitis with +3 or +4 cell in anterior chamber; Completion of informed consent; Older than 18 years; No history of topical drug consumption; No history of previous ocular surgery; Not pregnant or decision for pregnancy. Exclusion criteria: Exclusion request for any reason at any time; Lack of timely patient; Not compliant patient; The incidence of drug sensitivity

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Mean time to remission of intraocular inflammation. Timepoint: Each 72 hours until complete remission of intraocular inflammation. Method of measurement: with Slit Lamp and according to SUN Group criterion.	—

Secondary

Measure	Time frame
Incidence of ocular complications such as burning, Dryness and tearing. Timepoint: Each 72hours. Method of measurement: Ask from patient.;Intraocular pressure. Timepoint: Each 72hours. Method of measurement: with Goldman tonometer in mmHg.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Arjmand

Mashhad University of Medical Sciences

Arjmandm921@mums.ac.ir+98 51 3728 1401

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026