Furcation involvement class 2 mandible molars (periodontitis). Periodontal disease, unspecified
Conditions
Interventions
Intervention 1: Intervention group: allograft and membrane and simvastatin gel are used. After local anesthesia and incision in the target area, flap were reflected, debridemant was performed, then al
Treatment - Surgery
Intervention group: allograft and membrane and simvastatin gel are used. After local anesthesia and incision in the target area, flap were reflected, debridemant was performed, then allograft with sim
Control group: allograft with placebo gel. After local anesthesia and incision in the target area, flap were reflected, debridemant was performed, then allograft put in the defect, membrane adapted o
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1- presence at least 1 pair of first or second molar of mandible bilaterally accompanied with fraction involvement class 2 with less or equal 3 mm horizontal penetration of probe. 2- presence at least 2 mm keratinized gingiva around each tooth. Exclusion criteria: 1- smoking. 2- history of systemic disease. 3- pregnant or breast feeders. 4- history of antibiotic consumption within 2 months. 5- hx of periodontal treatment within 6 months. 6- hx of hypersensitivity to statins. 7- pt with statin treatments. 8- aggressive periodontitis. 9- tooth mobility grade 3. 10- pulp-pathology and incomplete RCT or PA lesion. 11- poor oral hygiene.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical Attachment Level. Timepoint: preoperative, during and 6 months post surgery. Method of measurement: probe and CBCT. | — |
Secondary
| Measure | Time frame |
|---|---|
| Recession. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe.;Bone Fill. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Probing pocket depth. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Horizontal penetration in the Furca. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe and CBCT.;Bleeding Index. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe.;Plaque Index. Timepoint: before Surgery- during Surgery- 6 month after. Method of measurement: Periodontal probe. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Farin Kiany Yazdy
Shiraz Dentistry School
Outcome results
None listed