Regional Anesthesia. Local Anesthetics
Conditions
Interventions
Intervention 1: Supraclavicular injection of 30 milliliter 0.5 percent Bupivacaine + 20 microgram Dexmedetomidine solution with ultrasound guidance. Intervention 2: Supraclavicular injection of 30 mil
Treatment - Drugs
Supraclavicular injection of 30 milliliter 0.5 percent Bupivacaine + 20 microgram Dexmedetomidine solution with ultrasound guidance
Supraclavicular injection of 30 milliliter 0.5 percent Bupivacaine + 0.2 milliliter Normal Saline solution (As a Placebo) with ultrasound guidance
Sponsors
Tehran University of Medical Sciences Vice Chancellor of Research
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:20-50 year old; Body Mass Index less than 35; American Society of Anesthesiologists class I,II; No Allergic drug history; Patient satisfaction and fill out the consent form Exclusion Criteria: Failed to supraclavicular block; Prolonged surgery more than 180 minutes; Cancel patients; Liver Disease; Diabetes Mellitus; Hypertension; taking Blood pressure medication; taking beta blocker medication; The incidence of surgical complication during surgery; Requires general anesthesia
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Arterial Pressure. Timepoint: In recovery (base line) then every 5 minutes after block, then every 5 minutes after starting surgery for 30 minutes, then every 15 minutes till end of surgery and in Departure time from recovery. Method of measurement: Millimeter Hg (Mercury) by non-invasive Manometer device. | — |
Secondary
| Measure | Time frame |
|---|---|
| Heart Rate per minute. Timepoint: In recovery (base line) then every 5 minutes after block, then every 5 minutes after starting surgery for 30 minutes, then every 15 minutes till end of surgery and in Departure time from recovery. Method of measurement: Cardiac Monitoring Device.;Respiratory Rate per minute. Timepoint: In recovery (base line) then every 5 minutes after block, then every 5 minutes after starting surgery for 30 minutes, then every 15 minutes till end of surgery and in Departure time from recovery. Method of measurement: Monitoring Device.;Arterial Oxygen Saturation. Timepoint: In recovery (base line) then every 5 minutes after block, then every 5 minutes after starting surgery for 30 minutes, then every 15 minutes till end of surgery and in Departure time from recovery. Method of measurement: Continious Pulse Oximetry.;Narcotics received in 24 hours. Timepoint: Total drug intake in first 24 hours after surgery. Method of measurement: Patient's file.;Time to First Analgesic Request. Timepoint: Time to first analgesic request. Method of measurement: Patient's file.;Onset of Sensory Block. Timepoint: 5-10-15 -30 minute intervals after injection. Method of measurement: Physical Examination by Physician (Pinprick test).;Onset of Motor Block. Timepoint: 5-10-15 -30 minute intervals after injection. Method of measurement: Physical Examination by Physician (Lovett Rating Scale).;Duration of Sensory Block. Timepoint: Every 10 minutes after full sensory block until complete return of sensation. Method of measurement: Physical Examination by Physician (Pinprick test).;Duration of Motor Block. Timepoint: Every 10 minutes after full motor block until complete return of motor function. Method of measurement: Physical Examination by Physician (Lovett Rating Scale). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Siamak Yoosefi Khanghah
Shariati Hospital, Anesthesiology Department
Outcome results
None listed