Regional anesthesia. Local anaesthetics
Conditions
Interventions
Intervention 1: second intervention group receives 30 ml hyperbaric bupivacaine along with 20 micro gram dexmedetomidine to perform regional anesthesia. Intervention 2: first intervention group receiv
Treatment - Drugs
second intervention group receives 30 ml hyperbaric bupivacaine along with 20 micro gram dexmedetomidine to perform regional anesthesia
first intervention group receives 30 ml hyperbaric bupivacaine along with 2 ml saline as placebo to perform regional anesthesia
second control group receives 30 ml hyperbaric bupivacaine along with 20 micro gram dexmedetomidine to perform regional anesthesia
first control group receives 30 ml hyperbaric bupivacaine along with 2 ml saline as placebo to perform regional anesthesia
Sponsors
Tehran University Of Medical Sciences Vice Chancellor Of Research
Eligibility
Sex/Gender
Male
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: inclusion criteria: (ASA) physical status class I and II; male; current smokers; aged between 18-60; scheduled for elective upper limb orthopedic surgery under supraclavicular nerve block. exclusion criteria: Patients with any contraindications to supraclavicular nerve block; patients with addiction to any substance other than opium and cigarettes; patients with known history of cardiac, respiratory, or psychological diseases; block failure of any nerve distributions (i.e. if the patient feel pain in those regions), the patient will be excluded from the study, even when the block is adequate to perform the operation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensory block onset. Timepoint: sensory block will be checked continuously after completion of injection until complete sensory and motor block. Method of measurement: pinprick test and a verbal rating scale from 100% (normal sensation) to 0 (no sensation).;Sensory block duration. Timepoint: after complete sensory block and every 15 minutes following the end of operation. Method of measurement: pinprick test and a verbal rating scale from 100% (normal sensation) to 0 (no sensation).;Motor block onset. Timepoint: motor block will be checked continuously after completion of injection until complete motor block. Method of measurement: Lovett rating scale.;Motor block duration. Timepoint: after complete motor block and every 15 minutes following the end of operation. Method of measurement: the Lovett rating scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: continuously monitoring while the surgery is performing. Method of measurement: manometer.;Diastolic blood pressure. Timepoint: continuously monitoring while the surgery is performing. Method of measurement: manometer.;Heart rate. Timepoint: continuously monitoring while the surgery is performing. Method of measurement: Monitoring.;Respiratory depression. Timepoint: continuously monitoring while the surgery is performing. Method of measurement: O2 saturation & Respiratory Rate.;Drug consumption in the 24 hours after surgery. Timepoint: patient need. Method of measurement: Medical records. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Maryam Taheri
Shariati Hospital, Anesthesilogy Department
Outcome results
None listed